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safe2268945 artist:swain89 pinkie pie266033 rarity225943 human269401 g42127739 ask-humans-from-equestria39 breasts416122 busty pinkie pie15148 cafe859 clothes679107 comic140637 comically missing the point67 cutie mark eyes337 female1910657 glasses95726 horn242770 horned humanization8434 humanized124489 marshmelodrama1037 miniskirt7232 misspelling3349 pinkie logic53 project mistletoe17 skirt60199 socks110826 striped socks29912 thigh highs77447 thigh socks1096 wingding eyes44383

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Background Pony #3944
Swain’s Pinkie Pie looks more like Whitney than a humanized Pinkie Pie thanks to her twintails and striped socks.
The CLaUD
Friendship, Art, and Magic (2018) - Celebrated Derpibooru's six year anniversary with friends.
Friendship, Art, and Magic (2017) - Celebrated Derpibooru's five year anniversary with friends.
Artist -

Definately NOT a bot!
It’s probabily just the stripes and the pigtails, but something about this pinkie just says Harley Quinn to me…
Grelrik

For those not entirely related with this kind of subject, PMS is more common in women over their 40 decades, it is strange to see it happen im a 16 yeard old girl even more strange to see it on 3 girls that happen to be friends.
BigMax
Fine Arts - Two hundred uploads with a score of over a hundred (Safe/Suggestive)
The End wasn't The End - Found a new home after the great exodus of 2012

Oh.  
Of course, Pinkie gets it immediately.
 
@PonyPon  
“A lady never has an uncouth thing such as ‘PMS’! She simply has her own, natural moods.”
Background Pony #D9E3
reading back the previous comics, Pinkie is 100% correct  
that is the biggest joke :p