this is before Pinkie Pie and Rarity join Fluttershy and Rainbow dash for a cry and Twilight too after Applejack said “nope I’m good and she said “then I am” that Twilight said as she join the mane 5 for a cry

No one cares applejack, just let it all out! Go on!

That time when her crush got back with his ex girlfriend and one of her best friends comforts her and cries on the inside when she cries on the outside.
 
Twi: sobbing  
AJ: There, there Sugarcube. It’s for the best.  
Twi: teary But I love him.  
AJ: Ah know, but you have to move on. Flash and Sunset are better for each other.  
Twi: If I can’t love him, then my life will suck.  
AJ: Don’t say that. You are really a very smart and amazing Pony. Your life can’t suck if your crush didn’t love you back. You’ve got me.  
Twi: Applejack…  
AJ: Don’t feel depressed. I am here and always be here for you.  
Twi: continues crying  
AJ: It’s alright. I might not be him, but I would love you as my bestest friend.  
Twi: Thank you… Applejack…

Twilight goodbye tank
 
Applejack shh it’s okay twilight I’m here

Twilight’s crying because she accidentally made a dog ear in a book.
 
“I’M TOO POWERFUL FOR MY OWN GOOD!! THAT POOR BOOK DIDN’T SEE IT COMING WÈÈÈÈÈÈÈÈHHHHHH”  
“Yeah…there there.”

“Yeah, ah’m cryin’ in the inside, sure…”