Blood for the Blood God!

Insanity

I want to pet this person on the head.

@Badman Giant  
Yup, Yup! That’s the one! :D

@Minus  
I think Black Eyes Blue was referring to this from Rainbow Rocks
 

do it for science!

@Black Eyes Blue  

 
Would love to know what you’re talking about. I’ve never seen Twilight look like this before. Is it a comic thing?

The Experiments of Twilight Sparkle

This pic is practically canon now! :P
 
Just needs the glasses…

Small Fugue  
Even more fitting music.

You have your work  
And nothing more!  
You are possessed -  
What is your demon?
 
You’ve never been  
This way before -  
Where is the fire  
You built your dream on?
 
There’s something strange,  
There’s something wrong.  
I see a change -  
It’s like when love dies.
 
I, who have known  
You for so long,  
I see the pain  
In your eyes!
 
There was a time  
You lived your life,  
And no one lived  
The way that you did !  
You had a plan,  
You chose your friends,  
You saw the world  
As very few did!
 
You had it all-  
The overall!-  
You seemed to know  
Just what to live for!
 
But now it seems,  
You don’t at all.  
You have your work-  
Nothing more ! …

I have achieved SCIENCE.

From the thumbnail I thought sue was missing her left arm, and it was just a blood-stained bandaged stump.

@SeraphimDawn  
There are quite a few vocaloid songs that are pretty dark… it’s awesome! XD

@SeraphimDawn  
Point, though I think the slasher smile wouldn’t work as well here.

@Background Pony #CB06  
The blood, insane face, and the coat.

@SeraphimDawn  
Because of the coat?  
Whatever the case, fantastic reference.

Twilight: “Here is that blood sample you wanted. It was a bitch to get.”

Well aren’t you a cute little mad scientist.

Twilight Sparkle: Science at all costs.

@OverlordScorpion
 

…That’s not Koolaid.

If you don’t know how to separate an enzyme, what makes you think I will by drinking it?

On second thought, I’m not thirsty, after all. I’ll just be running, now.