Sunset regaining her mobility (she’s 999 so it seems she’s officially reached her goal weight good for her)
AJ seems to be moving on from Rarity and will pursue a relationship with Rainbow (will most likely become a feeder since Rainbow’s been losing weight for some time now)
Rarity might find a way to cope with AJ and Rainbow’s relationship (chocolates and ice cream anyone?)
Pinkie and Fluttershy will maintain their relationship (nothing special comes to mind, Pinkie seems to be getting smaller and Fluttershy bigger)
And finally Twilight might finally surpass her weight limit one day (everybody besides Fluttershy has been losing weight so we might as well get compensated with a bigger Twilight in the future)